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National Institutes of Health

NIMH Pages about Depression

Learn more about Depression…

Clinical Trials Page

Find current studies on Depression…

Publications

Women and Depression: Discovering Hope
A booklet that describes the symptoms, treatment and factors contributing to depression that are unique to women.
Date: 2009
También disponible en Español
Looking at My Genes: What Can They Tell Me?
A fact sheet containing frequently asked questions about genome scans and genetic testing.
Date: 2008
Depression (Easy to Read)
An easy-to-read booklet on Depression that explains what it is, when it starts, how long it lasts, and how to get help.
Date: 2007
También disponible en Español
Depression
A detailed booklet that describes Depression symptoms, causes, and treatments, with information on getting help and coping.
Date: 2007
También disponible en Español
Men and Depression
A detailed booklet that describes what you need to know about depression in men: how it looks, how it feels, getting help, and getting better.
Date: 2005
También disponible en Español

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Science News

Long-term Depression Treatment Leads to Sustained Recovery for Most Teens
November 18, 2009 • Science Update
Long-term treatment of adolescents with major depression is associated with continuous and persistent improvement of depression symptoms in most cases, according to the most recent analysis of follow-up data from the NIMH-funded Treatment of Adolescents with Depression Study (TADS). The report, along with a commentary compiling the take-home messages of the study, was published in the October 2009 issue of the American Journal of Psychiatry.
NIH Encourages Depressed Moms to Seek Treatment for Themselves
November 13, 2009 • Science Update
Numerous studies have suggested that depression runs in families. Children of depressed parents are 2–3 times as likely to develop depression as compared to children who do not have a family history of the disorder. Other studies have shown that remission of depression in mothers is associated with improvements in psychiatric symptoms in their children. Despite all signs encouraging mothers to prioritize their own mental health, many suffer from untreated depression while managing treatment for their children’s emotional or behavioral problems.
Telephone-based Depression Treatment Program Effective While Cost Efficient
October 16, 2009 • Science Update
Patients who receive structured, telephone-based support to manage their depression gain significant benefits with only moderate increases in health care costs compared to those who receive usual care, according to an NIMH-funded analysis published in the October 2009 issue of the Archives of General Psychiatry.
New Approach to Reducing Suicide Attempts Among Depressed Teens
September 29, 2009 • Science Update
A novel treatment approach that includes medication plus a newly developed type of psychotherapy that targets suicidal thinking and behavior shows promise in treating depressed adolescents who had recently attempted suicide, according to a treatment development and pilot study funded by the National Institute of Mental Health (NIMH). The study, described in three articles, was published in the October 2009 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.
Combination Treatment for Psychotic Depression Holds Promise
August 07, 2009 • Science Update
A combination of an atypical antipsychotic medication and an antidepressant known as a selective serotonin reuptake inhibitor (SSRI) may be more effective in treating psychotic depression than an atypical antipsychotic alone, according to results from an NIMH-funded clinical study.

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Meeting Summaries

Perinatal Mood Disorders: Components of Care
May 07, 2009 – May 08, 2009
Bethesda, Maryland
A two-day meeting convened in May 2009 educated participants on essential components of care for women with perinatal mood disorders
Research Roundtable: Heterogeneity in Child and Adolescent Depression
February 18, 2008 – February 19, 2008
Washington, DC
The purpose of this workshop was to discuss empirical evidence for sources of heterogeneity in child and adolescent depression, evaluate the significance of known heterogeneity, and identify promising research directions in this area.
Benefits, Limitations, and Emerging Research Needs in Treating Youth with Depression
February 06, 2006 – February 07, 2006
Washington, DC
On February 6 and 7, 2006, experts in child and adolescent depression met in Washington, DC to review the state of the science of the treatment of youth depression and discuss approaches to further research.
Treating Children and Adolescents with Depression: Future Research Questions
February 01, 2006
Washington, DC
In February 2006, NIMH hosted this two-day workshop with the purpose of reviewing the evidence for benefits and risks of existing treatment interventions for youths suffering from depression, identifying knowledge gaps in need of further research, and discussing approaches to future research with respect to design, methods, and implementation.

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