Science News about Bipolar Disorder
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Science News about Bipolar Disorder
- Schizophrenia and Bipolar Disorder Share Genetic Roots
- July 01, 2009 • Press Release
A trio of genome-wide studies – collectively the largest to date – has pinpointed a vast array of genetic variation that cumulatively may account for at least one third of the genetic risk for schizophrenia. One of the studies traced schizophrenia and bipolar disorder, in part, to the same chromosomal neighborhoods. - Symptoms Persist as Bipolar Children Grow Up
- October 27, 2008 • Science Update
Bipolar disorder (BD) identified in childhood often persisted into adulthood in the first large follow-up study of its kind. - New Study to Evaluate Ways to Control Metabolic Side Effects of Antipsychotics
- October 01, 2008 • Science Update
A new NIMH-funded grant will examine ways to control the metabolic side effects associated with the use of the newer atypical antipsychotic medications in children with schizophrenia or bipolar disorder. - Family-Focused Therapy Effective in Treating Depressive Episodes of Bipolar Youth
- September 01, 2008 • Science Update
Adolescents with bipolar disorder who received a nine-month course of family-focused therapy (FFT) recovered more quickly from depressive episodes and stayed free of depression for longer periods than a control group, according to an NIMH-funded study published September 2008 in the Archives of General Psychiatry. - Largest Study of Its Kind Implicates Gene Abnormalities in Bipolar Disorder
- August 18, 2008 • Press Release
The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. - Mice Expressing Human Genes Bred to Help Unravel Mental Disorders
- June 26, 2008 • Science Update
New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMH’s Division of Neuroscience and Basic Behavioral Science. - Potential New Target Found for Developing Medications to Treat Bipolar Disorder
- June 20, 2008 • Science Update
Medications that target the protein BAG1, which regulates a process that can trigger symptoms in people who have bipolar disorder, may offer a new way of treating the disease, according to NIMH scientists. - New NIMH Research to Test Innovative Treatments for Children with ADHD
- June 05, 2008 • Science Update
Two new grants funded by NIMH will focus on novel and innovative approaches to treating children who have attention deficit hyperactivity disorder (ADHD). - Imaging Identifies Brain Regions and Chemicals Underlying Mood Disorders; May Lead to Better Treatments
- May 06, 2008 • Science Update
WASHINGTON, DC, May 6 — Recently developed imaging techniques allow the mapping of the brain circuits and chemical systems believed responsible for a range of mood abnormalities including depression and bipolar disorder, and hold promise for improved treatments, scientists say. - Bipolar Youths’ Misreading of Faces May be Risk Marker for Illness
- March 04, 2008 • Science Update
Youngsters with pediatric bipolar disorder and healthy peers who have first-degree relatives with bipolar disorder share the same difficulty labeling facial emotions, NIMH researchers have discovered. Reporting in the February 2008 online edition of the American Journal of Psychiatry, the scientists suggest that the facial emotion recognition impairment might be part of an inherited predisposition to the illness. - Tomorrow’s Antidepressants: Skip the Serotonin Boost?
- February 14, 2008 • Science Update
New research adds to evidence of potentially better molecular targets in the brain to treat depression and other mental disorders, according to NIMH-funded scientists. - Faster-Acting Medications for Bipolar Disorder’s Manic Phase May Be Feasible
- January 23, 2008 • Science Update
Scientists may be able to develop faster-acting medications for the manic phase of bipolar disorder, new research shows. - Mood Disorders Predict Later Substance Abuse Problems
- January 09, 2008 • Science Update
People with manic symptoms and bipolar disorder type II are at significant risk of later developing an alcohol abuse or dependence problem, a long-term study conducted in Switzerland confirms. The study was published in the January 2008 issue of the Archives of General Psychiatry. - Bipolar Disorder Phenome Database May Aid Search for Related Genes
- October 02, 2007 • Science Update
Early findings from the recently launched Bipolar Disorder Phenome Database were published in the August 2007 issue of the American Journal of Psychiatry. - Manic Phase of Bipolar Disorder Benefits from Breast Cancer Medication
- September 12, 2007 • Press Release
The medication tamoxifen, best known as a treatment for breast cancer, dramatically reduces symptoms of the manic phase of bipolar disorder more quickly than many standard medications for the mental illness, a new study shows. - Rates of Bipolar Diagnosis in Youth Rapidly Climbing, Treatment Patterns Similar to Adults
- September 03, 2007 • Press Release
The number of visits to a doctor's office that resulted in a diagnosis of bipolar disorder in children and adolescents has increased by 40 times over the last decade, reported researchers funded in part by the National Institutes of Health (NIH). - Studies Refine Understanding of Treatments for Bipolar Disorder
- September 01, 2007 • Science Update
Two new studies provide additional details on best practices for treating people with bipolar disorder, a sometimes debilitating illness marked by severe mood swings between depression and mania. - Bipolar Youth Show Distinct Pattern of Brain Development
- August 28, 2007 • Science Update
The first picturess of the brain changing before-and-after the onset of pediatric bipolar disorder reveal a distinct pattern of development, when compared to that seen in healthy youth or in childhood onset schizophrenia. - Parents' Diagnoses Help to Distinguish Childhood Bipolar Disorder from Severe Mood Dysregulation
- August 06, 2007 • Science Update
The parents of children who have bipolar disorder are more likely to have bipolar disorder themselves than the parents of children who have severe mood dysregulation (SMD). - NIMH Funds Research for Early Intervention in Childhood Bipolar Disorder
- June 04, 2007 • Science Update
NIMH recently approved funding to test the effectiveness of an early intervention in children at high risk for developing bipolar disorder. - Genetic Roots of Bipolar Disorder Revealed by First Genome-Wide Study of Illness
- May 08, 2007 • Press Release
The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows. - Bipolar Spectrum Disorder May Be Underrecognized and Improperly Treated
- May 07, 2007 • Press Release
A new study supports earlier estimates of the prevalence of bipolar disorder in the U.S. population, and suggests the illness may be more accurately characterized as a spectrum disorder. - Gene Knockout Unleashes Manic Mouse
- April 05, 2007 • Science Update
Mice engineered to lack a specific gene showed behaviors similar to human mania in a study funded in part by NIMH; they were hyperactive, slept less, appeared less depressed and anxious, and craved sugar, cocaine and pleasure stimulation. - Intensive Psychotherapy More Effective Than Brief Therapy for Treating Bipolar Depression
- April 02, 2007 • Press Release
Patients taking medications to treat bipolar disorder are more likely to get well faster and stay well if they receive intensive psychotherapy, according to results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), funded by the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH). - Study Sheds Light on Medication Treatment Options for Bipolar Disorder
- March 28, 2007 • Press Release
For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine. - Extreme Irritability: Is It Childhood Bipolar Disorder?
- February 01, 2007 • Press Release
Results of a new study may help improve the diagnosis and treatment of two debilitating childhood mental disorders — pediatric bipolar disorder (BD) and a syndrome called severe mood dysregulation (SMD). - Different Families, Different Characteristics — Different Kinds of Bipolar Disorder?
- January 03, 2007 • Science Update
People with bipolar disorder (BPD) tend to share similarities in certain characteristics with other members of their families, NIMH-funded researchers have shown. - Landmark Council Session Spotlights “Real World” Trials
- December 21, 2006 • Science Update
Principal investigators of NIMH's four large-scale clinical trials presented study results and their implications at the National Advisory Mental Health Council meeting on September 15, 2006. - New Research Helps to Improve Understanding of Bipolar Disorder in Youth
- October 24, 2006 • Science Update
Bipolar disorder may be hard to identify in children and adolescents for several reasons, including a lack of age-appropriate diagnostic guidelines and symptoms different than those commonly seen in adults with the disorder. - NIMH Researchers Discover Medication’s Antidepressant Potential
- October 02, 2006 • Science Update
A commonly used sedative and motion-sickness treatment shows promise as a fast-acting antidepressant, according to a study conducted by researchers at NIMH. - Bipolar Disorder Exacts Twice Depression’s Toll in Workplace, Productivity Lags Even After Mood Lifts
- September 01, 2006 • Press Release
Bipolar disorder costs twice as much in lost productivity as major depressive disorder, an NIMH funded study has found. - Obesity Linked with Mood and Anxiety Disorders
- July 03, 2006 • Science Update
Results of an NIMH-funded study show that nearly one out of four cases of obesity is associated with a mood or anxiety disorder, but the causal relationship and complex interplay between the two is still unclear. - Intermittent Explosive Disorder Affects up to 16 Million Americans
- June 05, 2006 • Press Release
A little-known mental disorder marked by episodes of unwarranted anger is more common than previously thought, a study funded by NIMH has found. - Fear Circuit Flares as Bipolar Youth Misread Faces
- May 29, 2006 • Press Release
Youth with bipolar disorder misread facial expressions as hostile and show heightened neural reactions when they focus on emotional aspects of neutral faces, NIMH researchers have discovered. - Lithium Blocks Enzyme To Help Cells’ Clocks Keep On Tickin’
- February 17, 2006 • Science Update
NIMH-funded researchers have discovered how lithium likely fixes body clocks gone awry, stabilizing sleep-wake cycles and other daily rhythms disturbed along with mood in bipolar disorder. - Largest Study to Date on Pediatric Bipolar Disorder Describes Disease Characteristics And Short-Term Outcomes
- February 08, 2006 • Science Update
Recent findings from the multi-site, NIMH-funded Course and Outcome of Bipolar Illness in Youth (COBY) study are helping to shape the understanding of three major subtypes of bipolar disorder that affect children and adolescents and how this diagnosis may affect them as adults. - Early Findings from Largest NIMH-Funded Research Program on Bipolar Disorder Begin to Build Evidence-Base on Best Treatment Options
- February 01, 2006 • Science Update
Findings from an NIMH research program on bipolar disorder provide much needed long-term data on the chronic, recurrent course of the disorder, and begin the work of building an evidence-base on the best treatments for those with the disorder. - Mutant Gene Linked to Treatment-Resistant Depression
- December 13, 2004 • Science Update
A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI). - Stress Impairs Thinking Via Mania-Linked Enzyme
- October 29, 2004 • Press Release
An errant enzyme linked to bipolar disorder, in the brain’s prefrontal cortex, impairs cognition under stress, an animal study shows. - Mental Illness Genetics Among Science’s Top “Breakthroughs“ for 2003
- December 22, 2003 • Press Release
Research on the genetics of mental illness, most of it NIMH-funded and much of it in the Institute’s own laboratories, was named the #2 scientific "breakthrough of the year" by Science magazine in its December l9, 2003, issue. - NIMH Awards $22.6 Million for Center for Collaborative Research on Mental Disorders
- July 01, 2003 • Press Release
The National Institute of Mental Health (NIMH) has funded a five-year, $22.6 million Center for Collaborative Genetic Studies on Mental Disorders at Rutgers, The State University of New Jersey. - Lithium Shows Promise Against Alzheimer’s in Mouse Model
- May 21, 2003 • Press Release
An enzyme crucial to formation of Alzheimer’s plaques and tangles may hold promise as a target for future medications, suggest studies in mice and cells. - NIMH Awards Howard University $6.5 Million
- January 25, 2002 • Press Release
Howard University Hospital Department of Psychiatry in the College of Medicine (HUCM) has been awarded $6.5 million from the National Institute of Mental Health (NIMH) for a five-year project to implement and develop research studies pertaining to mood and anxiety disorders.
