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- Newer Antipsychotics No Better Than Older Medications in Reducing Schizophrenia-related Violence
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July 11, 2008
Science Update
Antipsychotic medications can reduce the risk of violence among people with schizophrenia, but the newer atypical antipsychotics are no more effective in doing so than older medications. - Common Mechanisms May Underlie Autism’s Seemingly Diverse Mutations
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July 10, 2008
Press Release
Many of the seemingly disparate mutations recently discovered in autism may share common underlying mechanisms, say researchers supported in part by the National Institute of Mental Health (NIMH), a part of the National Institutes of Health (NIH). The mutations may disrupt specific genes that are vital to the developing brain, and which are turned on and off by experience-triggered neuronal activity. - Abnormal Surge in Brain Development Occurs in Teens and Young Adults with Schizophrenia
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July 8, 2008
Science Update
Schizophrenia may occur, in part, because brain development goes awry during adolescence and young adulthood, when the brain is eliminating some connections between cells as a normal part of maturation, results of a study suggest. The new report appears online July 8, 2008 in Molecular Psychiatry. - NIMH Schizophrenia Initiative Featured in Biological Psychiatry
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July 3, 2008
Science Update
An NIMH initiative to fill the gap between advances in basic cognitive neuroscience and practical clinical applications for patients with schizophrenia is the topic of the July 1, 2008 issue of Biological Psychiatry. It contains eight articles on the Cognitive Neuroscience Approaches to the Treatment of Impaired Cognition in Schizophrenia (CNTRICS) initiative, including a commentary, and descriptions of meetings related to the effort. - HIV-associated Neurological Disease Prevalent in Asia-Pacific Region
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July 1, 2008
Science Update
A new study finds a significant rate of HIV-related neurological disease among HIV-positive populations living in the Asian-Pacific region. - Couples-based Intervention May Limit HIV Transmission in African Countries
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June 27, 2008
Science Update
A shift to a couples-based intervention for married and cohabiting couples in urban Zambia and Rwanda could prevent up to 60 percent of new HIV infections that would otherwise occur, according to an NIMH-funded study published June 27, 2008, in The Lancet. - Mice Expressing Human Genes Bred to Help Unravel Mental Disorders
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June 26, 2008
Science Update
New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMH's Division of Neuroscience and Basic Behavioral Science. - New Grant Supports Stem Cell-Derived Model of Autism-Related Illness
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June 26, 2008
Science Update
For the first time, researchers are developing a test tube model of Rett syndrome, a debilitating autism-like illness, in neurons derived from human embryonic stem cells. The study, recently funded by a grant from NIMH’s Division of Neuroscience and Basic Behavioral Science, addresses a crucial gap in understanding the workings of the rare autism spectrum disorder. - Antipsychotic Medications May Ease Some Alzheimer’s Symptoms, Not Others
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June 23, 2008
Science Update
Antipsychotic medications may lessen symptoms like hostility and aggression in patients with Alzheimer’s disease, but do not appear to lessen other symptoms or improve quality of life, according to a recent analysis of data from the NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness Alzheimer’s Disease (CATIE-AD) study. The analysis was published online ahead of print June 2, 2008, in the American Journal of Psychiatry. - New Grant Aims to Overcome Obesity in People with Serious Mental Illness
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June 20, 2008
Science Update
A new grant funded by NIMH will test the effectiveness of a promising intervention designed to help people with serious mental illness (SMI) who are overweight or obese lose weight and keep it off.
