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- New Schizophrenia Trial: Does Method of Administering Medication Make a Difference?
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September 5, 2006
Science Update
A new clinical trial is testing whether an injection of a long-lasting antipsychotic medication every two weeks results in better adherence to treatment and better outcomes among people with schizophrenia than do oral medications taken daily.
- Subsequent Treatment Strategies for Persistent Depression Yield Modest Results
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September 1, 2006
Science Update
Patients with treatment-resistant depression had a modest chance of becoming symptom-free when they tried different treatment strategies after two or three failed treatments, according to results from the nation's largest real-world study of depression.
- Brain Changes Mirror Symptoms in ADHD
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July 19, 2006
Science Update
The severity of attention deficit hyperactivity disorder (ADHD) symptoms in youth appears to be reflected in their brain structure, recent NIMH-supported brain imaging studies are finding.
- New Factors Identified for Predicting Violence in Schizophrenia
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July 18, 2006
Science Update
A study of adults with schizophrenia showed that symptoms of losing contact with reality, such as delusions and hallucinations, increased the odds of serious violence nearly threefold.
- Targeted Therapy Halves Suicide Attempts in Borderline Personality Disorder
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July 3, 2006
Science Update
Dialectical Behavior Therapy (DBT) reduced suicide attempts by half compared with other types of psychotherapy available in the community in patients with borderline personality disorder, an NIMH-funded study has found.
- Switching to a Third Antidepressant Medication May Prove Helpful to Some with Treatment-Resistant Depression
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July 1, 2006
Science Update
The next wave of results from the nation's largest real-world study of treatment-resistant depressionshows that patients had a moderate chance of becoming symptom-free when they switched
to a third antidepressant medication, following two previously unsuccessful medication attempts.
- Antidepressant Does Not Reduce Risk Of Relapse Among Patients With Anorexia Nervosa
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June 14, 2006
Science Update
An NIMH-funded study has concluded that the antidepressant medication fluoxetine (Prozac) is no more effective than placebo in preventing relapse among patients with anorexia nervosa who had achieved a healthy weight during inpatient or day-program treatment.
- Intermittent Explosive Disorder Affects up to 16 Million Americans
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June 5, 2006
Press Release
A little-known mental disorder marked by episodes of unwarranted anger is more common than previously thought, a study funded by NIMH has found.
- Depression Rates Are Lower in Children Whose Mothers Are Successfully Treated
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May 9, 2006
Science Update
When women treated for depression become symptom-free, their children are less likely to be diagnosed with depression, according to a study published in the March 22/29 issue of the Journal of the American Medical Association.
- Studies Offer New Information About Treatment Choices for Schizophrenia — Phase 2 Results
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April 1, 2006
Science Update
A national clinical trial comparing clozapine with other new-generation antipsychotic medications for the treatment of chronic schizophrenia has shown that people who switched to clozapine from their first medication because it failed to manage symptoms adequately were twice as likely to continue treatment as patients who switched to other antipsychotic medications.