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Genetic Variation May Influence Response to Depression Treatment
February 20, 2008 • Science Update
Variations in a gene known as TREK1 may explain some forms of treatment-resistant major depression, according to a new study analyzing genetic data.
Team Care for Depressed Older Adults Cuts Overall Medical Costs
February 14, 2008 • Science Update
A team approach to depression treatment for older adults, already shown to be effective, is also less expensive than usual care.
Family-centered Intervention Effectively Reduces Risky Behavior Among Hispanic Youth
December 20, 2007 • Science Update
A family-centered program that improves parent-child dynamics and family functioning is more effective at discouraging Hispanic youth from engaging in risky behavior than programs that target specific behaviors.
Behavioral Therapy Effectively Treats Children with Social Phobia
December 17, 2007 • Science Update
A behavioral therapy designed to treat children diagnosed with social phobia helped them overcome more of their symptoms than the antidepressant fluoxetine (Prozac).
Behavioral Program May Stabilize Stress Hormone Patterns in Foster Children
November 30, 2007 • Science Update
An intervention designed to enhance family interaction and improve foster parenting skills may benefit young foster children who had experienced extreme neglect or maltreatment in early life.
Depressed Adolescents Respond Best to Combination Treatment
October 1, 2007 • Press Release
A combination of psychotherapy and antidepressant medication appears to be the most effective treatment for adolescents with major depressive disorder—more than medication alone or psychotherapy alone.
Family Involvement and Focused Intervention May be Key to Helping Teens with Bulimia
September 17, 2007 • Science Update
Family-based treatment for adolescent bulimia nervosa (FBT-BN) is more effective than an individual-based therapy called supportive psychotherapy (SPT) in helping teens overcome bulimia according to an NIMH-funded study.
Studies Refine Understanding of Treatments for Bipolar Disorder
September 1, 2007 • Science Update
Two new studies provide additional details on best practices for treating people with bipolar disorder, a sometimes debilitating illness marked by severe mood swings between depression and mania. The two studies are part of the NIMH-funded Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
Bipolar Youth Show Distinct Pattern of Brain Development
August 28, 2007 • Science Update
The first picturess of the brain changing before-and-after the onset of pediatric bipolar disorder reveal a distinct pattern of development, when compared to that seen in healthy youth or in childhood onset schizophrenia.
Suspect Schizophrenia Genes Act Together to Thwart Working Memory
August 28, 2007 • Science Update
Two gene variants implicated in schizophrenia interact to degrade the brain's ability to process information, NIMH researchers have discovered. The interaction impaired working memory — retaining information from moment to moment. Such thinking problems are a hallmark of this severe mental illness that affects about one percent of the population.
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