Clinical Trials
Post-Traumatic Stress Disorder (PTSD)
Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Examining the Effectiveness of an Early Psychological Intervention to Prevent Post-Traumatic Stress Disorder.
Interventional study. This study will examine the use of prolonged exposure therapy on people who have recently experienced a trauma to prevent them from developing post-traumatic stress disorder. Ages 18-65. Location in Atlanta, GA.
- Treating People With Post-Traumatic Stress Disorder With Cognitive Behavioral Therapy for Insomnia.
Interventional study. This study will test the effectiveness of cognitive behavioral therapy for insomnia in treating sleep disturbances in people with post-traumatic stress disorder. Ages 18-65. Location in San Francisco, CA.
- Examining Written Disclosure as a Treatment for Post-Traumatic Stress Disorder.
Interventional study. This study will test the effectiveness of writing about a traumatic incident to treat post-traumatic stress disorder in people who have been in car accidents. Ages 18 and over. Location in Boston, MA.
- Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder.
Interventional study. This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation. Ages 18-65. Location in New York, NY.
- Effectiveness of a Web-Based Intervention for Guardians of Children Whose One Parent Has Murdered the Other.
Interventional study. This study will determine whether a specialized Web site geared for the guardians of children whose one parent has murdered the other can increase guardian capabilities, reduce guardian stress, and improve child behavior and mental health. Ages 18 and over. Location in Charlottesville, VA.
- Effectiveness of Cognitive Behavioral Couples Therapy for Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of cognitive behavioral couples therapy designed for post-traumatic stress disorder in reducing symptoms of post-traumatic stress disorder and in improving relationship functioning. Ages 18-75. Location in Boston, MA.
- Effectiveness of Propranolol For Treating People With Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of propranolol in reducing symptoms of distress in people with post-traumatic stress disorder. Ages 18-50. Location in New York, NY.
- Effectiveness of Trauma-Focused Cognitive Behavioral Therapy in Treating Children With Post-Traumatic Stress Disorder.
Interventional study. This study will compare the effectiveness of trauma-focused cognitive behavioral therapy versus standard care in treating children with post-traumatic stress disorder. Ages 8-18. Location in New York, NY.
- Cognitive Behavioral Therapy for Treating Recently Abused Women With Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of a brief cognitive behavioral treatment, Helping to Overcome PTSD through Empowerment, in treating abused women with post-traumatic stress disorder who are living in shelters. Ages 18 and over. Location in Akron, OH.
- Evaluating the Effects of Stress in Pregnancy.
Evaluation study. This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy. Ages 18-45. Location in Atlanta, GA.
- Cognitive Behavioral Treatment for Post-Traumatic Stress Disorder in People With Additional Serious Mental Illnesses.
Interventional study. This study will evaluate the effectiveness of tailored cognitive behavioral therapy in treating post-traumatic stress disorder in people with additional mental illnesses. Ages 18 and over. Locations in New Brunswick, NJ; Newark, NJ; Monmouth Junction, NJ.
- Comparing Behavioral Therapies for Treating Adolescents With Post-Traumatic Stress Disorder Related to Sexual Abuse.
Interventional study. This study will evaluate the comparative effectiveness of prolonged exposure therapy and client centered therapy in treating adolescents with post-traumatic stress disorder related to childhood sexual abuse or assault. Ages 13-18. Location in Philadelphia, PA.
- Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders.
Evaluation study. This study is intended to help develop new MRI imaging techniques for studying mood and anxiety disorders. Ages 18-50. Location in Bethesda, MD.
- Effectiveness of Virtual Reality Exposure Therapy and D-Cycloserine to Treat Iraq War Veterans With Post-Traumatic Stress Disorder.
Interventional study. This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans. Ages 21-65. Location in Atlanta, GA.
- Group Intervention for Interpersonal Trauma.
Interventional study. This study will assess the acceptability and effectiveness of a six-session, modular, repeating group for low-income women who have symptoms of depression and/or post-traumatic stress disorder following interpersonal trauma exposure. Ages 18-70. Location in Washington, DC.
- Patient-Centered Collaborative Care for Preventing Post-Traumatic Stress Disorder After Traumatic Injury.
Interventional study. This study will evaluate the effectiveness of patient-centered collaborative care that combines behavioral therapy and drug therapy as compared to usual care in reducing symptoms of post-traumatic stress disorder in people who have survived a traumatic injury. Ages 18 and over. Location in Seattle, WA.
- Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors. Ages 18 and over. Location in Seattle, WA.
- Psychobiological Mechanisms of Resilience to Trauma.
Evaluation study. This study will evaluate brain changes and psychological characteristics of people who are resilient to trauma. Ages 18 and over. Locations in Washington, DC; Bethesda, MD.
- Brain Function in Mentally Ill Adolescents.
Evaluation study. The purpose of this study is to use brain imaging technology to examine the brain activity of adolescents with post-traumatic stress disorder (PTSD) and/or major depressive disorder (MDD) before and after treatment. Ages 7-18. Locations in Newark, DE; Bethesda, MD.
Search ClinicalTrials.gov for other NIH studies on Post-Traumatic Stress Disorder (PTSD).
